Determination of 99 Mo Contamination in a Nuclear Medicine Patient Submitted to a Diagnostic Procedure with 99 m Tc
نویسندگان
چکیده
Tc is a radionuclide widely used for imaging diagnosis in nuclear medicine. In Brazil it is obtained by elution from 99 Mo-Tc generators supplied by the Nuclear Energy Research Institute (IPEN). The elution is carried out in radiopharmacy laboratories located in hospitals and clinics. Depending of the quality of the generator and conditions of use during the elution process, Mo can be extracted from the column of the generator, becoming a radionuclidic impurity of the eluate used for the obtention of the radiopharmaceutical to be administered to the patient. Mo emits high-energy photons and beta particles and its presence degrades the quality of the image and unnecessarily increases the radiation dose delivered to the patient. An in-vivo measurement technique was developed to verify the occurrence of internal contamination by Mo in nuclear medicine patients. Direct measurements were made in a volunteer who underwent myocardial scintigraphy with Tc-sestamibi. The results indicated the presence of internal contamination of the patien by Mot. The activity was tracked for several days, and an assessment of the radiation dose from the contaminant Mo was made.
منابع مشابه
Determination of 99Mo contamination in 99mTc elute obtained from 99Mo / 99mTc- generator
Background: 99mTc is a widely used radioisotope in nuclear medicine centers which is obtained by elution from Mo-99/Tc-99m generators. Usually the generators are either supplied by the Iran Atomic Energy Agency or by private companies from foreign countries. In this study we have measured 99Mo contamination in 99mTc elute from different generators in a period of one year. Materials and...
متن کاملPoly zirconium chloride (PZC) as an efficient adsorbent for 99 MO
This radionuclide is almost exclusively produced from the decay of its parent 99Mo. 99mTc is themost available and important nuclide used as a diagnostic agent in nuclear medicine. To develop anewly practical 99mTc generator using ( n,y ) 99Mo, an inorganic polymer adsorbent has beendeveloped framed with oxygen-zirconium-chlorine bonds with a high adsorption of Mo, Thepolyzirconium adsorbent wa...
متن کاملDiversification in the Supply Chain of (99)Mo Ensures a Future for (99m)Tc.
The uncertain availability of (99m)Tc has become a concern for nuclear medicine departments across the globe. An issue for the United States is that currently it is dependent on a supply of (99m)Tc (from (99)Mo) that is derived solely by production outside the United States. Since the United States uses half the world's (99)Mo production, the U.S. (99)Mo supply chain would be greatly enhanced i...
متن کاملProduction and Supplies of 99mo: Lessons Learnt and New Options within Research Reactors and Neutron Sources Community
During the past few years, the research reactor (RR) topic has occupied the centre stage being the major factor in the crisis faced world over in the supplies of medical isotopes, molybdenum-99 in particular. It is therefore an important aspect for discussion at the quadrennial international conference on research reactors organised by the IAEA. The November 2011 IAEA conference at Rabat, Moroc...
متن کاملPreparation of Tc-sn-colloid kit for liver-spleen imaging [Persian]
When Tc-99m-sulfur colloid was introduced as an ideal liver-spleen agent in nuclear medicine, many other types of colloids followed by different manufacturers. They hoped to find a suitable colloidal agent, contrary to sulfur colloid, which is easy to use, and less sensitive to the low contamination of aluminum ions. One of this type of colloid agents, is Tc-99-tin-colloid which is prepar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2005